Platelets are anuclear cell fragments derived from bone marrow megakaryocytes that safeguard vascular integrity by forming thrombi at sites of vascular injury.Although the early events of thrombus formation--platelet Wheel Support adhesion and aggregation--have been intensively studied, less is known about the mechanisms and receptors that stabiliz
The issues of constructing high-rise, primarily residential, buildings have a great social significance.Not every plot of land, acquired in the Russian Federation is suitable for high-rise construction.Therefore, every construction company that plans to erect a multi-apartment building, a high-rise office building, or a skyscraper must take into ac
Combinatorial library of novel benzenesulfonamides was docked (Schrodinger Glide) into Premium Tee mycobacterial carbonic anhydrase (mtCA II) and human (hCA II) isoforms with an aim to find drug candidates with selective activity on mtCA II.The predicted selectivity was calculated based on optimized MM-GBSA free energies for ligand enzyme interacti
Increasing complexity of societal questions requires participatory processes that engage Foot Care Collection with capable participants.We adopted Horellis’ stance on participation as not an isolated event but a constant communication between different groups that can be assured by using enabling tools.We applied the Capability Approach to fr